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Chapter 2. How Vitamin D Works

This talk about how Vitamin D works


References in this Section


Nuclear hormone receptors and gene expression.
Aranda A, Pascual A. Nuclear hormone receptors and gene expression. Physiol Rev. 2001 Jul;81(3):1269-304.

Vitamin D receptor and retinoid X receptor interactions in motion.
Barsony J, Prufer K. Vitamin D receptor and retinoid X receptor interactions in motion. Vitam Horm. 2002;65:345-76.

Vitamin D supplements in pregnant Asian women: effects on calcium status and fetal growth.
Brooke OG, Brown IR, Bone CD, Carter ND, Cleeve HJ, Maxwell JD, Robinson VP, Winder SM. Vitamin D supplements in pregnant Asian women: effects on calcium status and fetal growth. Br Med J. 1980 Mar 15;280(6216):751-4

Intrauterine vitamin D nutrition and postnatal growth in Asian infants.
Brooke OG, Butters F, Wood C. Intrauterine vitamin D nutrition and postnatal growth in Asian infants. Br Med J (Clin Res Ed). 1981 Oct 17;283(6298):1024.

Overview of general physiologic features and functions of vitamin D.
DeLuca HF. Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr. 2004 Dec; 80(6 Suppl):1689S-96S.

Effects of vitamin D metabolites on intestinal calcium absorption and bone turnover in elderly women.
Devine A, Wilson SG, Dick IM, Prince RL. Effects of vitamin D metabolites on intestinal calcium absorption and bone turnover in elderly women. Am J Clin Nutr. 2002 Feb;75(2):283-8.

Genomic and proteomic approaches for probing the role of vitamin D in health.
Fleet JC. Genomic and proteomic approaches for probing the role of vitamin D in health. Am J Clin Nutr. 2004 Dec; 80(6 Suppl):1730S-4S.

Calcium absorptive effects of vitamin D and its major metabolites. J Clin Endocrinol Metab.
Heaney RP, Barger-Lux MJ, Dowell MS, Chen TC, Holick MF. Calcium absorptive effects of vitamin D and its major metabolites. J Clin Endocrinol Metab. 1997 Dec;82(12):4111-6.

Functional indices of vitamin D status and ramifications of vitamin D deficiency.
Heaney RP. Functional indices of vitamin D status and ramifications of vitamin D deficiency. Am J Clin Nutr. 2004 Dec; 80(6 Suppl):1706S-9S.

Skin as the site of vitamin D synthesis and target tissue for 1,25-dihydroxyvitamin D3. Use of calcitriol (1,25-dihydroxyvitamin D3) for treatment of psoriasis.
Holick MF, Smith E, Pincus S. Skin as the site of vitamin D synthesis and target tissue for 1,25-dihydroxyvitamin D3. Use of calcitriol (1,25-dihydroxyvitamin D3) for treatment of psoriasis. Arch Dermatol. 1987 Dec;123(12):1677-1683a.

Dietary calcium and vitamin D intake in elderly women: effect on serum parathyroid hormone and vitamin D metabolites.
Kinyamu HK, Gallagher JC, Rafferty KA, Balhorn KE. Dietary calcium and vitamin D intake in elderly women: effect on serum parathyroid hormone and vitamin D metabolites. Am J Clin Nutr. 1998 Feb;67(2):342-8.

Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid X receptor alpha ligand-binding domain.
Lengqvist J, Mata De Urquiza A, Bergman AC, Willson TM, Sjovall J, Perlmann T, Griffiths WJ. Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid X receptor alpha ligand-binding domain. Mol Cell Proteomics. 2004 Jul;3(7):692-703. Epub 2004 Apr 8.

Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption.
McKane WR, Khosla S, Egan KS, Robins SP, Burritt MF, Riggs BL. Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption. J Clin Endocrinol Metab. 1996 May;81(5):1699-703.

Maternal 25-hydroxyvitamin D and parathyroid hormone concentrations and offspring birth size.
Morley R, Carlin JB, Pasco JA, Wark JD. Maternal 25-hydroxyvitamin D and parathyroid hormone concentrations and offspring birth size. J Clin Endocrinol Metab. 2006 Mar;91(3):906-12. Epub 2005 Dec 13.

Causes of secondary hyperparathyroidism in a healthy population: the Tromso study.
Saleh F, Jorde R, Sundsfjord J, Haug E, Figenschau Y. Causes of secondary hyperparathyroidism in a healthy population: the Tromso study. J Bone Miner Metab. 2006;24(1):58-64.

Vitamin D: more than a "bone-a-fide" hormone.
Sutton AL, MacDonald PN. Vitamin D: more than a "bone-a-fide" hormone. Mol Endocrinol. 2003 May;17(5):777-91. Epub 2003 Mar 13.

Vitamin D3 analogs stimulate hair growth in nude mice.
Vegesna V, O'Kelly J, Uskokovic M, Said J, Lemp N, Saitoh T, Ikezoe T, Binderup L, Koeffler HP. Vitamin D3 analogs stimulate hair growth in nude mice. Endocrinology. 2002 Nov;143(11):4389-96.

Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety.
Vieth R. Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J Clin Nutr. 1999 May;69(5):842-56.

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